Ortho substituents complicate due to steric influence as well. Meta substituents are not in through resonance with the carbonyl group of benzoic acid. Electron withdrawing group increases dissociation while electron donating decrease dissociation of benzoic acid. The influence is studied at a specific temperature 25 0 C and a specific solvent like water. Thus the relation can be expressed as. The relation between free energy and equilibrium constant is.

Using the above relation and substituting in the first equation. Introduction 1. The Hammett equation 1. The reaction constant p 1. The substituent constant a 1. The a 0 scale 1. The effect of solvent on a values 1. Problems 2 Elucidation of reaction mechanisms 2. Introduction 2. Modified substituent constants 2. The a- substituent constant 2. Diagnosis of reaction mechanisms 2. Aromatic nucleophilic substitution 2. Aromatic electrophilic substitution 2. Nucleophilic aliphatic substitution 2. Condensations of carbonyl compounds with amine derivatives 2.

Free radical and multicentre reactions 2. Conclusion 2. Problems 1 I I 7 n 17 20 24 27 27 27 28 31 33 38 40 49 57 63 66 67 3 The separation of inductive, resonance and steric effects; application of the Hammett equation to aliphatic systems 3. Introduction 3. The evaluation of inductive effects 3.

The evaluation of resonance effects 69 69 70 75 83 V 3. Acta, 48, Google Scholar. Veschambre and A. Veschambre, G. Dauphin, and A. Toma, Coll. Noyce and M. Jorgenson, J. Dessy and J. Kim, J. Matthews and E. Imafuku, S. Nakama, and H. Matsumura, Tetrahedron, 26, Google Scholar. Czerwinska-Fejgin and W. Polaczkowa, Roczniki Chem. Malawski and T. Schindler, Personal communication, Google Scholar. Jones and N.

Mueller, J. Bren, E. Medyantseva, and V. Minkin, Reakts. Soedin 5, ; EE, Google Scholar. Minkin, Yu. Zhdanov, and E. Medyantseva, Dokl Akad. Grekov and M. Marakhova, Ukr. Donohue, R. Scott, and F. Yeh and H. Socha, F. Socha, J. Socha and M. Kubota, Nippon Kagaku Zasshi, 84, ; Chem. Fischer and I. Litvinenko, R. Cheshko, and A. Gofman, Zh. Litvinenko and R. Cheshko, Zh. Cheshko, and R. Popova, Reakts. Popova, and A. Popov, Reakts. Litvinenko, V. Dadali, and L.

Savchenko, Reakts. Fischer and J. Bolton, F. Hall, and I.

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## Hammet equation-Linear free energy relation

Reece, J. Hill and L. Schmookler, J. Malysheva, and V. Stairs, Can. Ellis, W. Fyfe, R. Rutherford, A. Fischer, and J. Mann, and J. Fuchs and A. Nisbet, Amer. Fischer, G. Leary, R. Gutbezahl and E. Petrov and L. Bykova, Reakts. Hradil and V. Chvalovsky, Coll. Kondo, T. Matsui, and N. Tokura, Bull. Japan, 42, Google Scholar. Wilputte-Steinert, P. Fierens, and H. Hannaert, Bull. Beiges, 64, Google Scholar. Smith and D. White, J. Smith, K. Lum, J. Kirby, and J. Posposil, J. Meyers, E. Warwas, and C. Farlow and R. Moodie, J. Walter and R. Becker, Ann. De Filippo and F.

Momicchioli, Tetrahedron, 25, Google Scholar. Liler, Nature, , Google Scholar. Kresze, W. Schramm, and G. Cleve, Chem.

## The Hammett Equation

Hancock and C. Falls, J. Gosselck, H. Barth, and L. Gosselck and H. Barth, Z. Saunders and R. Koehler, W. Sandstrom, and E. Cordes, J. Kooyman, R. Bickel, Proc. Weten- s chap. Bender, Chem. Ogata and I. Tabushi, Bull. Japan, 34, Google Scholar. Sneen, J. Carter, and P. Kay, J. Roberts, E. McElhill, and R. Armstrong, J. Roberts and E. McElhill, J. Roberts and C. Regan, J. Bordwell and G. Cooper, J. Sheppard, J. Pollet, and A. Pollet, R. Beiges, 75, 40 Google Scholar. Peterson, D. Chevli, and K. Sipp, J. Okamoto, T.

Inukai, and H. Exner and E. Streitwieser and J. Humphrey, J. Wilson, N. Gore, J. Sawbridge, and F. Cardenas-Cruz, J. Herbst and M. Jacox, J. Wilson, A. Briggs, J. Sawbridge, P. Tickle, and J. Zuckerman, J. A , Google Scholar. Stewart and L. Walker, Can. Bystrov, A. Stepanyants, and Yu. Fialkov, Zh. Khim34, ; EE, Google Scholar. Lifshits, L. Naroditskaya, and E. Kozlova, Reakts. Sheppard and R. Henderson, J. Landgrebe and R. Rynbrandt, J. Eaborn, A. Thompson, and D. B , ; Google Scholar.

Jones and V. Jones, Tetrahedron Lett. Hahn, T. Corbin, and H. Shechter, J. Lichtin and H. Leftin, J. Polaczkowa, N. Porowska, and B. Dybowska, Roczniki Chem. Ruskie and L. Glover, J. Porowska, W. Polaczkowa, and S. Kwiatkowska, Roczniki Chem. Bodor and A. Webb, and E. Orda, L. Bystrov, and A. Stepanyants, Zh. Fawcett and W. Voloshchuk, L. Syrova, and V. Case, R. Price, N. Ray, H. Roberts, and J.

Wright, J. White, R. Schlitt, and D. Gwynn, J. Weinstein, A. Bluhm, and J. Sousa, J. Nishiguchi and Y. Iwakura, J. Benkeser and H. Krysiak, J. Eaborn and S. Parker, J. Buchman, M. Grosjean, and J. Nasielski, Helv. Acta, 47, Google Scholar. Streitwieser, J. Bassindale, C. Eaborn, D. Walton, and D.

Young, J. Organometal Chem. Serjeant, Austral. Howard and J. Brock, J. Data, 6, Google Scholar. Antos, D. Zahradnik, Coll. Hall, and R. Kan, J. Habraken, Rec. Ryan and A. Tsvetkov, D. Lobanov, M. Makhamatkhanov, and M. Kabachnik, Tetrahedron, 25, Google Scholar. Baldwin, M. Cheng, and G. Homer, J. Freedman and H. Wepster, Personal communication, reference Google Scholar. Price and J. Hydock, J. Backer, Rec. Meyers, Gazz. Meyers, B. Cremonini, and L. Beishline, J. Zollinger and C. Acta, 39, Google Scholar.

Listy, 59, Google Scholar. Robinson and K. Aug, J. Chan, J. Miller, and F. Stansfield, J. Little, R. Berry, and P. Kannan, J. Nesmeyanov, E. Perevalova, S. Gubin, K. Grandberg, and A. Kozlovsky, Tetrahedron Lett. Traylor and J. Ware, J. Packer, J. Vaughan, A. Wilson, and E.

Wong, J. Gassman and A. Fentiman, Tetrahedron Lett. Rakshys, R. Taft, and W. Schindlbauer and W. Prikoszovich, Chem. Prikoszowich and H. Schindlbauer, Chem. Taft and J. Rakshys, J. Pews, J. Lindberg, Arkiv Kemi, 32, Google Scholar. Little, C. Reilley, J. Johnson, and A. Sanders, J. Vaughan and W. Martin and W. Brause, Chem. Hayashi and R. Shibata, Bull. Williams, E. Martin, and W. Chem ,, 31, Google Scholar. Maciel, J. Hine and W. Bailey, J. Ingold, Quart. Scott, Tetrahedron Lett. Wolfsberg, Tetrahedron Lett.

Grunwald and E. Schubert, R. Murphy, and J. Robins, Tetrahedron, 17, Google Scholar. Clement, J. Naghizadeh, and M. Rice, J. Baker and W. Nathan, J. Lichtin, P. Rowe, and M. Puar, J. Shiner and C. Verbanic, J.

- A modification of the Hammett equation for predicting ionisation constants of p-vinyl phenols..
- A modification of the Hammett equation for predicting ionisation constants of p-vinyl phenols..
- Supplementary files.

Kreevoy and H. Bryson, J. Koppel, V. Maremae, and A. Schwarzenbach and E. Rudin, Helv. Acta, 22, Google Scholar. Freedman and G. Acta, 39, 46 Google Scholar.

### Related content in Oxford Reference

Szmant and C. Harmuth, J. Reiser, Chem. Listy, 52, Google Scholar. Kessler, Chem. Liotta and D. Pinholster, J. D , Google Scholar. Monack, J. Bunnett, F. Draper, P. Ryason, P. Noble, R. Tonkyn, and R. Zahler, J. Bunnett, H. Moe, and D.